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Crosslinked hyaluronic acid dermal fillers found to improve skin barrier function



A 2016 study has found that crosslinked hyaluronic acid (not yet the kind typically used in most dermal filler applications at your local friendly cosmetic dermatologist) improve the skin’s barrier function among other extra benefits besides anti-ageing.

What is the barrier function of the skin?
The skin has one job: keep your insides inside and the world out. That is, to act as a barrier. The barrier function of skin is much-discussed in dermatology circles, since any breakdown of this barrier function means the world can creep in and irritate your skin.

A pilot study considered a dermal filler product that uses crosslinked hyaluronic acid, finding it to be superior to non-crosslinked (linear) low and high weight hyaluronic acid dermal filler products when it came to increasing skin hydration, keeping the skin strong, and improving its barrier function.

This is good news for anyone using hyaluronic acid dermal fillers, since these dermal fillers are already great for your skin, providing hydration and an increase in collagen production for anti-ageing. Advances in how these dermal filler products function is only of benefit, since their use will become more widespread across dermal filler products with better skin outcomes for your skin.

This is one of the first studies to show that there are in fact differences in hyaluronic acid formulations in terms of how the skin behaves. Crosslinked hyaluronic acid was found to enhance the longevity of the product inside the skin, while also doing its job of alleviating fine lines and wrinkles, softening skin and filling out areas that have lost volume. The researchers also found that the crosslinked varieties of hyaluronic acid may also be useful in topical preparations, adding much-needed hydration.

Study findings:

  • Crosslinked hyaluronic acid dermal filler was a more efficacious moisture retainer than low molecular weight hyaluronic acid
  • Crosslinked hyaluronic acid was a better barrier-type moisturiser than high molecular weight hyaluronic acid
  • Crosslinked hyaluronic acid significantly improved the skin barrier structure and function by keeping more moisture in the skin

Dermal fillers have come a long way, baby
Hyaluronic acid continues to transform the dermal filler landscape, with manufacturers putting new and innovative products to market regularly. Hyaluronic acid is a versatile ingredient in dermal filler products, being low-allergic and helping the skin stay hydrated, stronger, more protective, and also stimulating collagen production.

Hyaluronic acid acts as a transporter fluid between the skin cells and blood vessels, meaning skin cells have more resources delivered to them when there is an abundance of hyaluronic acid in the skin.

Our Melbourne clinic offers an array of effective dermal filler treatments to enhance your natural features, while helping to rejuvenate your skin and keep it vibrant.

Contact us to discuss your dermal filler needs at our Melbourne clinic.


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